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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de246eb624403f2e9ab33c1fa92cc9063c94280c767d2d608afbaff35fc07f2' 
  AND token = 'ry5Ki9RBc9zO9QpAjsX4Gn+QvyMI3PrJ8/kaTvI2zO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}