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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e649ee1e6451ad4c0de898bdb03060b5c81ed1430877a2928b27b769d8157c22' 
  AND token = 'lYJNdPC1B+T6b8ONjz8pKw8ssQRpk2zQjqAF/gsguKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}