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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181a35f8173bafd7de2688089bb4a4426237df77171d3ac8d61991115541d898' 
  AND token = 'Pkbu6trokr0t0rCsqxeZnnSLleAdT5P/vaqByvKXU9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}