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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f59a73b4cb9d0dc982f2aa3f457c69abc956b66a1ca705b24df25baace92019a' 
  AND token = 'IiSMhwELdQ9lvfsYOoWCVBa4ZTjNdHwU+ypT7r6Oav4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}