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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9395be5437ef25a0eef37b30decf0e103a5974ad5a184df1c0b30c9b4ac07bd' 
  AND token = 'VQnYj9GJqAoojSaCAOYvCPF5M7OpSCJCbp+Xb+xGrS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}