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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7672675349e6715530834c6c8b75cf01170af7ec0c056d6052d58e37267f2b04' 
  AND token = 'R192TuyaDN5+zPtCmCH2Hpn9XyxZRXEOeH1u+yxL3IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}