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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '790dea919f4bd2a1bbdde1f17b3cfe6ff494c0468dab0de928b5ffdaa4186b17' 
  AND token = 'N/nL3wYcd37VPUwGyEvAXp8HXJ98xmshF1Ml/eYhhgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}