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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0112e9026ef0e18a3fe94b8b334f03c86e598c34bc88927c3815d3c784f12980' 
  AND token = '8l/U1p2YW6EueGcPgLBXQz11E+qUIjThpR14rZHx0Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}