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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dca1c7e2658cca51714515b07cbc4db4e03856cb5cbd9b141bfc8a0542bf4f52' 
  AND token = 'loBvqNtDUqY8DD88GNaLrZxWYW4O0AzrvLty2ZZvwu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}