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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8bcbb0fbe8efa7fd6054865197bc2356b865e9a92d44e4abe26f25a1511c8c' 
  AND token = 'ZFxlnnxPru7PhO4A32+4Uo+moOARGI3glOJTvk5VeIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}