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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bc3903172412d90cca2957a3e39047a2911bd2a78cd17a61f2f24079080e886' 
  AND token = 'hOgWOvKzjyMGIOygEyLVgaUKy9cjDnx1vKABaD84fWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}