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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8e52e588c4ecdf4324bc3d4db5196a1ade739892f4b328c55e6f8256c25d00e' 
  AND token = 'yPDPhxIi7TzRGeRyax5I0tlOAGtiaeLvyuW018a4hUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}