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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44cf1d7283fec37b2a452bf8dfc74dd14b2a1669c1e1e4f69ebbde9e387b6eee' 
  AND token = 'HET4kXKGPDjAH+yHqnYM4k0MNQeRe1G/CKBuKFHKdoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}