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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebe63d91cd67f1939515fce0ef3c8a7e2dd14f066b00cc766f989c130fd0eaf0' 
  AND token = 'tdk+BL6Q0jsIfV1EE450x2XC3DLCoOXKKElPBheCXVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}