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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '227ca27d5c2837ea17dc1d62d24c56d3506a25dab92381207622ded81b0bd1c7' 
  AND token = '9OEZcnXJ4fk7qGlyFETU2XZTMZWS/cmq3969lGd+w2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}