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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b27f19a4b7ee0127d40db9e6cf552a7ccde8ecc9375f1312f6cfac4060f4c31c' 
  AND token = 'hOaXIxIhB/qq+ll5cVGC8f9D82FeIpEgWGbPSAwx0I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}