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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66b8a5ee72c14af3b27e377477a19ff1031262c4abf0964c32b34fc777192c35' 
  AND token = 'eYSrpx3oXHEAL1wMQ/EODgB8Jvz2Sn6cLhWr+2qVoWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}