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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad942d0c70be4f9b50aa150f2803cd9ab1e0646d6d9180b846664467b7682ce' 
  AND token = 'Gm4TUG7D5ZfP7qD3IG38F0CIypLQSJcZxjXJBA+yRUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}