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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e75cf8353000c92f485e954740aa0fade01c22d74f9dac21909a0d002bfb595' 
  AND token = 'Yq6SgVX1feWardi5qyP7PHHQdp4L1IcAEBpWZLelf9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}