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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbd5a4593e136c044c9bb4b2255f2d4823d5a9c4bfa7253257f92dd4e72305f3' 
  AND token = 'Ob+UsAlrdV8ONLXbrek5M2Y18tN7cuHHQko1fiGMI50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}