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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66fc58272438eb67d47e4f79967456595f8591fd9f844ff1312456005c0be15' 
  AND token = '+8xuWnN+SENvEyJ0y5AxAxAMXWvU+DlhRANzjk4LZ/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}