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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19f4b82d4d941d77cf84f8f7bdb431dd22a4ad1bcc264904f17248d2d1576502' 
  AND token = 'FXAGZcA8aj5lcZyCkw+IQGbHTLSg0EJvp2hWtD4PpD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}