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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4b6dc63bd33b9decef2765229ae87a0a311f9e31c21d46cc4f8f30182a0859' 
  AND token = 'x4Qhym2lnYVV7GrEoG9ZWoELF0ViVwb/gc3S77NbzaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}