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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6f0a579fba80de3d7a2689f64798724e031e72ed7d060b5cec9032404579ba' 
  AND token = 'u2y+1AoeFBxitGpN+iXw10I6FjBgCARjd6xgEZFQ6AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}