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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422e218388acc892db5b3adf28543355d51408059421be676342ef909257cca0' 
  AND token = 'oUna2o75XR9kHoBn+skmXx/tmIriyswhLPc4qM87USw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}