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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdd17597cf4f45001c342717021c787d93230f62951af757fe2a2eb15c28c799' 
  AND token = 'D6Lt6+4wzZn7gQ4lXonK6uD2nhAVSbYTryTmlI3lq5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}