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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bd9875aa8b72871c256cc8409560f8307b99d79926a31883df61f1beb070b4' 
  AND token = 'Jn5C1It3kWs4LkBK632aKs2xTL7+yYltP+onzMy1OWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}