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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ee2c2c47e9693ba2ec2c5161b3bdf520a2421ad55f462b95ca0b246ce56dfe9' 
  AND token = '0PXlGVB553i8VJC33lXlxr7iHrRRX1Dx2dAK0QgJalo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}