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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '272434e7942d0dd30857d131be9001fb027422a010e9c45d6166ceccd6a51d1a' 
  AND token = '+gquZnmbfcyJQRe3L7CbA12aXcmXFhWBR/hopyu/58s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}