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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7da25ff3bf22d1f528383cc58af38246266debb970b5a93f0d8d3bffa2d82e5' 
  AND token = '1Y65Hj1Fm/+IboM5so9/kB72Rbv3K37oKqY43CLg+Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}