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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eda8a4834ce69aeb5d37ec4906a215832fc9d8964818df31ee5cda62a4888c0' 
  AND token = 'UmFhDYV2BhyFXHIjlYcwEdA4ryT5TBmr6rSRfoc/cSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}