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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '039d60e350ac62708b83ce0852c4f4d7c28b754dc37c78a60cf3e8d09d79b129' 
  AND token = '81olat3iME7bxXUrPkMBQhYBaVuUkQJQppr/9/QoB2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}