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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f74919458d312a971ba2cce2709fdf3b1d7797d3bbbb451214f18da6f3ea7c' 
  AND token = 'S/Ci87HfUxVX7QcCh5Gi9sWEBpTbxQgFmVX9r/dWKyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}