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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb229aa832d35c074cbf797d86ad6b37f2eb57a4882ddeaa7fd819bd60f4487' 
  AND token = 'fKdJtSN+3hopf2YtYLLYWzYKusSH5hYlZlLH7v33T68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}