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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e499ef75f835c094b5a53a0730b2ecb4e13c23085cefecf7a70fbb2dc6d8af00' 
  AND token = '0Ou9Oq4FsxABIbFXJCSP87bheAE6tiI1jWXmqo+9E3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}