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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b437d79698ff5f6d4ca153fccba1d59a6e928d5a9b7d95a108b3e425bd910927' 
  AND token = 'qXnCYANqcIbMN7yA9xurmDTZ3ny8IVFrutIIPyEOYQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}