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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b497a1cee6237d75d59ccdf33a35d954c472b21de70cb1d874891d36b2d33903' 
  AND token = 'reqo1sijjQo8XWIpfVD1djCpIuUxdGvs+aFG/dE/yjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}