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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de20c83bbc68a7e553e5bb2eb81e1c8b149ef4c91a4156c0ede4f077db2287df' 
  AND token = 'DPr1sI8/0fe6doUlY5kKJTIK2TsEd3VSTDFp/PLm4yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}