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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b85b0e57eff4c3e4dcdf648166a1637d39d634e661e88084dcf218b947977da' 
  AND token = 'NMQ6cZ6lURZOmUzpgzsK2yIxie3xqiaj3m/VCjeglJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}