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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e40b48e2ba82d71d2b0746ed740aed407234075d8bc459fd990b4a28cb3b61' 
  AND token = '7aJdJ9O2yc1kWqRd81BCHdGErN2Yabolkj859DpNE30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}