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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad7752e270df62bae3132c42b0dec3a6018d1816b20bff64d24afebac000124' 
  AND token = 's5Va/BhDz4Xd8x2PgYxIQxmYlDIBLK30NbqYSWRFrVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}