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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a8f29226d566a78e07366cafce82eec2c24d2515c5f748bea992bf98d8e258b' 
  AND token = 'xng4d/k4USDGN9EhrxxgmkNsYM+2TfYACAtTbS61XG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}