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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b2daa43bf14d5cadbc33192e4d26556f04a020d0298cda3ef76ec8c69cc9c6' 
  AND token = 'ECB8dP9J8O9i62zB3aEFbRXdD6NbOxx/1ZibYOMGK2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}