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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04e0a24c8dd0ea4ec05acf23ce5e52bcda30770a3e23c3d273e9b8e2af767426' 
  AND token = '6FCjS6v3uJCufbkt9RB9c8CoxQ/vnfNfl4SAwEjGhiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}