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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1e568a3be3aadd949647a38ced381294b4ddd3266d595cdfb7b3cf5fd0a1195' 
  AND token = 'srwNAUSmLWkEZEULO+9ZM6Bt7jXeDCvmQgxyWTrE4qE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}