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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89fbbf7f4de48237565f88cc2706640203e49eadf3298c07fdfb9dda0f96cdb2' 
  AND token = 'bTk+ASIPnAUlMBhOVBrkdY1N9yB7G8EBHo1qEKOOTu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}