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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf7c1c3eec2c5cf28819c4b8c508876aa4b83765eb3a7789b13ec60da824a384' 
  AND token = 'oam5x9i+t0OhRECVuy13zb6XHTIB7Xz6DtpIjhlRz58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}