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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da0eb1f0d403d216093be0e65c8a26a71852c10f5bf170287b7ee7e2b3604195' 
  AND token = '+c6ISXF2PNf5rYCGprZVoc/eG7V8C3UEgotXCR4TiFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}