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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7428fa6fe6cb1eacb57ba940250d6ce38a0f551bcdc2750d9f9c25016fbb263' 
  AND token = 'OfT+W+9y4WLTRlf6k4/SELqxO1mUK+jbwrD/ph9CKnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}