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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d43bdb34b17bff2223bec5772981e7348196c43dac662054aca80108c6bf2b' 
  AND token = '02Vr9x0kc8Dpp4IjJhWTWxlll8FvuB+1+WcDnwAz46A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}